Definitions of abbreviations found throughout the PTSD-Repository.

Learn about this resource that brings together data from over 300 published studies on a wide range of PTSD treatments and how you can use it.

The purpose of this project was to identify and abstract data from randomized controlled trials (RCTs) of posttraumatic stress disorder (PTSD) interventions to support the development of a publicly accessible data repository by the National Center for Posttraumatic Stress Disorder.

The Technical Brief and Evidence Tables (Appendix E & F) are included in the downloadable .zip file. For more information, visit AHRQ's page: https://effectivehealthcare.ahrq.gov/products/ptsd-pharm-treatment/research

The PTSD-Repository is a comprehensive database of PTSD trials. The PTSD-Repository allows clinical, research, education, and policy stakeholders to understand current research on treatment effectiveness and harms, and enable informed decisions about future research, mental health policy, and clinical care priorities. This report updates the studies and variables included in the PTSD-Repository to include recently published trials, interventions targeting comorbid PTSD/SUD (substance use disorder), variables related to comorbidities such as suicide and SUDs, and risk of bias (ROB) assessment.

The Comparative Effectiveness Review (Update Report) and Evidence Tables (Appendix E, F-1, & G-1) are included in the downloadable .zip file. For more information, visit AHRQ's page: https://effectivehealthcare.ahrq.gov/products/ptsd-repository-expanded/research

Study Interventions for randomized controlled trials included in the NCPTSD's PTSD-Repository.

Each record is an arm of the study, labeled as A, B, C, or D.

Values abstracted as not applicable ("NA") or not reported ("NR") from the study are null values (empty cells).

Population Characteristics for Randomized Controlled Trials included in the NCPTSD's PTSD Repository.

Values reported as "NA" or not reported "NR" by the study are null values (empty cells).

The Study Interventions dataset includes information about each of 861 specific treatment arms that were studied in all 389 RCTs. Each study arm was coded to indicate the type of intervention or comparison condition. This dataset includes the study-level Study Class as well as individual variables for each category of treatment, coded as Yes or No for each arm. Study arm treatment category variables are as follows: Pharmacotherapy (as well as a subclass such as antidepressant, antianxiety, etc.); Psychotherapy (as well as a subclass to identify trauma-focused or non-trauma-focused therapy); Complementary and Integrative Health (CIH; as well as a subclass such as relaxation or meditation); Nonpharmacologic Biological; Nonpharmacologic Cognitive; Collaborative Care; Other Treatments; Control

The Study Intervention dataset also includes information on the format of the treatment (individual, group, couples, mixed); treatment delivery method (in person, by phone, by video, technology alone, technology assisted, written or mixed); dose or amount of treatment and, treatment completion and adherence. Use this dataset to learn about treatment studies of a particular type

Each record is an arm of the study, labeled as A, B, C, or D. Values abstracted as not applicable ("NA") or not reported ("NR") from the study are null values (empty cells).

Learn how to find data of interest and get started using the platform features of the PTSD-Repository.

The Harms dataset includes information on serious adverse events and participant withdrawals from the studies due to adverse events. Adverse events are reported as the percent of participants within a treatment group that experienced an adverse event or who withdrew from the study. Detail on the specific adverse event or reason for withdrawal is provided when available. This dataset also reports on the percentage of patients who attempted or completed suicide (when available).

Values abstracted as "NA" or "NR" from the study are represented as null values/empty cells in this dataset.

Study level variables like military status and percent female are included for filtering purposes.

This story outlines the organization scheme for the PTSD-Repository dataset and coding rules--decisions made about variables and response items.