The Study Interventions dataset includes information about each of 861 specific treatment arms that were studied in all 389 RCTs. Each study arm was coded to indicate the type of intervention or comparison condition. This dataset includes the study-level Study Class as well as individual variables for each category of treatment, coded as Yes or No for each arm. Study arm treatment category variables are as follows: Pharmacotherapy (as well as a subclass such as antidepressant, antianxiety, etc.); Psychotherapy (as well as a subclass to identify trauma-focused or non-trauma-focused therapy); Complementary and Integrative Health (CIH; as well as a subclass such as relaxation or meditation); Nonpharmacologic Biological; Nonpharmacologic Cognitive; Collaborative Care; Other Treatments; Control

The Study Intervention dataset also includes information on the format of the treatment (individual, group, couples, mixed); treatment delivery method (in person, by phone, by video, technology alone, technology assisted, written or mixed); dose or amount of treatment and, treatment completion and adherence. Use this dataset to learn about treatment studies of a particular type

Each record is an arm of the study, labeled as A, B, C, or D. Values abstracted as not applicable ("NA") or not reported ("NR") from the study are null values (empty cells).

The PTSD Outcome Comparisons Between Treatment Arms dataset includes the results of all between-group comparisons on PTSD outcomes. The omnibus test and effect size are provided, followed by pairwise comparisons for any study with more than 2 treatment arms. Results are provided for PTSD severity, loss of diagnosis and clinically meaningful change for studies that reported these outcomes. Use this dataset to look at changes in PTSD resulting from 2 or more treatments.

Values abstracted as NA or NR (not reported) from the study are empty cells (null) in this data set.

The Sample Characteristics dataset includes information on the participants who are included in the studies. This information is provided at the study level—meaning, data are not broken down into the specific treatment arms such as the intervention or control groups. Use this dataset if you want to learn more about the number of participants in the study; inclusion and exclusion criteria related to substance use and suicidality; baseline clinical characteristics such as PTSD severity, trauma type, military status, and comorbidities; and, basic demographic information such as age, gender or race for the sample as a whole (not individual participants). Visualizations made from this dataset will be based on the 389 RCTs included in the PTSD-Repository. Values reported as "NA" or not reported "NR" by the study are null values (empty cells). Data is at the study level.

The Study Characteristics dataset includes basic information about study design. In addition to study class, the dataset includes clinical setting, whether the study looked at PTSD symptom clusters, whether there were any subgroup analyses, type of diagnostic measure used (e.g., diagnostic interview, self-report), and provider credentials. Use this dataset to better understand the variety of RCT designs employed, compare studies by study class or to identify gaps in the literature for potential new RCTs. Visualizations made from this dataset will be based on the 389 RCTs included in the PTSD-Repository. Values reported as "NA" or not reported "NR" by the study are null values (empty cells). Data is at the study level.

The PTSD Outcomes Within Each Treatment Arm dataset includes information on how PTSD was measured and at which timepoint. Descriptive information is provided on which measure was used, the statistical approach to measuring change in PTSD, how PTSD was defined and the definitions of loss of diagnosis and clinically meaningful change, if these variables were included in the study.

Results in this dataset are provided for each treatment arm, and do not include comparisons across the arms (which can be found in the PTSD Outcome Comparisons Between Treatment Arms dataset described below). PTSD baseline mean score and standard deviation are provided as well as the within-treatment change from baseline. Within-group effect size is also included. The percent of participants who achieve loss of PTSD diagnosis and the percent who achieve clinically meaningful response are included for studies that reported these outcomes.
Use this dataset to learn about changes in PTSD within a specific treatment. For example, what is the change in Clinician Administered PTSD Scale score across all study arms of a specific treatment type? From the visualization, you can filter by PTSD measure of interest and type of treatment.

Values abstracted as not applicable ("NA") or not reported ("NR") by the study are null values (empty cells).

Suicide Continuous Outcomes compared between intervention groups.

Values abstracted as "NA" or "NR" from the study are represented as null values/empty cells in this dataset.

Study level variables like military status and percent female are included for filtering purposes.

Identifying information about each study, including citation, PubMed ID, PTSDPubs ID, ClinicalTrials.gov ID, and funding source(s).

The Other Outcomes dataset includes information on whether the trial includes measures of depression, anxiety, substance use, sleep, anger, quality of life and functioning. Results in this dataset are provided for each treatment arm. The name of the measure is included as well as the between-group effect sizes. Use this dataset to learn how about the effects of PTSD treatments on other outcomes.

Values abstracted as not applicable ("NA") or not reported ("NR") from the study are null values (empty cells).

Study level variables, like military status and percent female, are included for ease of filtering. These columns are not individual arm or arm comparison level data.

Definitions of abbreviations found throughout the PTSD-Repository.

The Harms dataset includes information on serious adverse events and participant withdrawals from the studies due to adverse events. Adverse events are reported as the percent of participants within a treatment group that experienced an adverse event or who withdrew from the study. Detail on the specific adverse event or reason for withdrawal is provided when available. This dataset also reports on the percentage of patients who attempted or completed suicide (when available).

Values abstracted as "NA" or "NR" from the study are represented as null values/empty cells in this dataset.

Study level variables like military status and percent female are included for filtering purposes.